A shadow market for unapproved weight-loss drugs is being driven by TikTok fitness influencers and sellers on communication apps, according to new investigations.
The experimental drug, which is still in clinical trials, is being advertised by social media influencers for its alleged weight-reducing properties. Followers are urged to message these profiles directly for source information, while also obtaining promotional offers.
Additionally, a flourishing market exists on messaging services, where communities with thousands of members share comparison photos, injection guides and claims of next-day British shipping. Vendors market the substance there before directing buyers to other platforms for transactions.
This medication is an investigational injectable developed by American pharmaceutical company Eli Lilly. The drug targets three intestinal hormones – glucagon-like peptide-1, GIP and pancreatic hormone. Preliminary studies indicate it could assist individuals reduce up to a quarter of their body weight. Nicknamed the “triple G”, the substance is being promoted online as the successor to Ozempic.
Nevertheless, doctors and pharmacists have cautions that the sale of what is still an unapproved drug in the United Kingdom is worrisome and could lead to individuals administering products of unknown origin.
Some professionals stated the demand for retatrutide could be linked to the rising price of approved weight loss treatments such as Mounjaro.
Marketing the unapproved drug on TikTok or messaging apps is illegal in the United Kingdom, as it is an unapproved drug that cannot be marketed or supplied for human use under the Human Medicines Regulations 2012.
Some content creators attempt to sidestep the rules by calling to the substance as a “research chemical” or citing it as “not for human consumption”. Retatrutide is not a controlled drug, but promotion and distribution can still breach medicines, marketing, and consumer laws, potentially leading to fines, prosecution or prison.
According to TikTok, the platform has taken down problematic content and banned associated keywords and query recommendations. The company said it was committed to maintaining the platform safe and allocating resources in strengthening enforcement strategies.
Research also found communities with up to 9,000 participants selling retatrutide using the platform's integrated search feature, which functions like a public directory. Typing “retatrutide” immediately displays channels with numerous of members, populated with images of slimming results, glowing reviews and step-by-step instructions for mixing or injecting at home.
Within minutes of joining one community, a seller posted contact information, where most purchases take place. The vendor provided an instruction manual and guaranteed shipping within 48 hours. When asked whether the substance was authentic, one vendor said: “You can’t be sure.” Another provided a photo of a alleged laboratory certificate. None asked about weight, health issues or past usage.
Inside these groups, messages show black plastic parcels with Royal Mail labels, stating to contain new batches. One message stated: “It took eight of us to load them this morning.”
Buyers can select between dry substance containers, mixed at home with purified liquid, or pre-filled injectors usually priced at 160 pounds for 20 milligrams. When asked how long a injector should last, sellers give conflicting responses ranging from a several days to “depends on your body”.
A representative for the messaging service stated it actively monitored dangerous content on its service including material that encouraged the “misuse of controlled medications”. The organization added that it eliminated “millions of pieces of harmful content each day”.
“Individuals are administering substances they can’t verify. Even if the research behind retatrutide is sound, these digital versions may not contain what they claim,” stated Jason Murphy, the director of pharmacy at a pharmacy service.
A medical professional of Asda Online Doctor connected the increase in demand to recent price rises for authorized slimming medications such as Mounjaro. “With costs rising, individuals are turning to online platforms. But fake injections are highly risky. You cannot know what’s contained or whether the environment they were produced in was sterile,” she said.
Her staff has previously encountered individuals injured by self-injection from unverified sources. “We understand the frustration, but purchasing from messaging apps or communication platforms is taking chances with your health,” stated the doctor. “These materials could be impure or incorrectly dosed.”
A spokesperson from Eli Lilly stated the substance was in phase 3 research studies and had not been reviewed or approved by any regulatory agency globally. “Consequently at this point no one can market [it] for personal consumption,” they explained, adding that any product “misleadingly claiming itself as a company investigational product not yet authorized … may subject patients to potentially significant health risks”.
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